The HCK Polyclonal Antibody (CAB2083) is a valuable tool for researchers studying the HCK protein, a critical regulator of immune cell function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the HCK protein, this antibody allows for the detection and analysis of HCK in various cell types, making it ideal for investigations in immunology and cancer research.HCK is a member of the Src family of kinases and is involved in signaling pathways that regulate immune cell activation and differentiation.
Dysregulation of HCK activity has been linked to various diseases, including cancer and autoimmune disorders. Therefore, understanding the role of HCK in immune system function is essential for the development of targeted therapies for these conditions.Overall, the HCK Polyclonal Antibody is a valuable asset for researchers seeking to unravel the complex mechanisms underlying immune cell regulation and disease pathogenesis. Its specificity and sensitivity make it a powerful tool for studying HCK and its potential implications for therapeutic interventions in immunology and oncology.
Product Name:
HCK Rabbit Polyclonal Antibody
SKU:
CAB2083
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human HCK (NP_001165600.1).
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Purification Method:
Affinity purification
Gene ID:
3055
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HL-60 cells, using HCK antibody (CAB2083) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
