HCK Rabbit Polyclonal Antibody (CAB2083)
- SKU:
- CAB2083
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | HCK Rabbit Polyclonal Antibody |
SKU: | CAB2083 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human HCK (NP_001165600.1). |
Sequence: | MGCM KSKF LQVG GNTF SKTE TSAS PHCP VYVP DPTS TIKP GPNS HNSN TPGI REAG SEDI IVVA LYDY EAIH HEDL SFQK GDQM VVLE ESGE WWKA RSLA TRKE GYIP SNYV ARVD SLET EEWF FKGI SRKD AERQ LLAP GNML GSFM IRDS ETTK GSYS LSVR DYDP RQGD TVKH YKIR TLDN GGFY ISPR STFS TLQE LVDH YKKG NDGL CQKL SVPC |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | JTK9; AIPCV; p59Hck; p61Hck; HCK |
Positive Sample: | HL-60 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Golgi apparatus, Lipid-anchor, Lysosome, Membrane, Nucleus, caveola, cytoskeleton, cytosol, cytosol, focal adhesion, podosome membrane, secretory vesicle. |
Calculated MW: | 60kDa |
Observed MW: | 65kDa |
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Purification Method: | Affinity purification |
Gene ID: | 3055 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |