The Hck Polyclonal Antibody (CAB14537) is a valuable tool for researchers studying the Hck protein, a key player in signaling pathways involved in immune responses and cell growth. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications.Hck is a member of the Src family of kinases and is known to play a critical role in regulating immune cell function, particularly in the context of inflammation and immune activation. By targeting Hck, researchers can gain insight into the mechanisms underlying immune system modulation and potentially uncover new targets for therapeutic intervention in conditions such as cancer and autoimmune diseases.
The Hck Polyclonal Antibody is suitable for use in various cell types and can enable researchers to detect and analyze levels of the Hck protein in their experimental samples. Its application in immunology and cancer research makes it an essential tool for understanding the role of Hck in disease and developing novel treatment strategies.
Product Name:
HCK Rabbit Polyclonal Antibody
SKU:
CAB14537
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 324-505 of human HCK (NP_001165600.1).
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Purification Method:
Affinity purification
Gene ID:
3055
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HCK Rabbit pAb (CAB14537) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
