The HCFC1R1 Polyclonal Antibody (PAC040674) is a crucial tool for researchers studying the HCFC1R1 protein, a key regulator of gene expression and transcriptional activation. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting HCFC1R1 in human samples, making it suitable for Western blot applications. By binding to HCFC1R1, this antibody enables precise detection and analysis of the protein in a variety of cell types, making it an essential component for investigations in molecular biology and gene regulation studies.
HCFC1R1, also known as host cell factor C1 regulator 1, is involved in various cellular processes such as chromatin remodeling, transcriptional regulation, and cell cycle control. Its role in modulating gene expression implicates it in the development of diseases such as cancer, neurological disorders, and developmental abnormalities. By understanding the function of HCFC1R1, researchers can uncover potential therapeutic targets and pathways for treating these conditions.
Antibody Name:
HCFC1R1 Antibody (PACO40674)
Antibody SKU:
PACO40674
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Host cell factor C1 regulator 1 protein (1-119AA)
Immunohistochemistry of paraffin-embedded human lung cancer using PACO40674 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver cancer using PACO40674 at dilution of 1:100.
Background:
Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
HCFC1R1: Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 16p13.3
