The HCFC1 Polyclonal Antibody (CAB16871) is a valuable tool for research involving the HCFC1 protein, a key regulator of gene expression and cellular function. This antibody, raised in rabbits, is highly specific and responsive to human samples, making it ideal for use in Western blot applications. By binding to the HCFC1 protein, this antibody enables researchers to detect and analyze HCFC1 expression in various cell types, providing insights into its role in cellular processes.HCFC1 is known for its involvement in transcriptional regulation and chromatin remodeling, making it a critical player in gene expression and cellular differentiation.
Its importance in these processes makes it a target of interest in studies related to developmental biology, cancer research, and neurological disorders. The HCFC1 Polyclonal Antibody offers researchers the ability to study HCFC1 expression and function, furthering our understanding of its role in various biological processes.
Product Name:
HCFC1 Rabbit Polyclonal Antibody
SKU:
CAB16871
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human HCFC1 (NP_005325.2).
This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Purification Method:
Affinity purification
Gene ID:
3054
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HCFC1 antibody (CAB16871) at 1:500 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.