The HCCS Polyclonal Antibody (CAB7490) is a valuable tool for researchers investigating the HCCS protein, which is involved in mitochondrial function and plays a crucial role in energy production within cells. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.HCCS, also known as holocytochrome c synthase, is essential for the maturation of cytochrome c, a key component of the mitochondrial respiratory chain. Dysregulation of HCCS has been linked to various diseases, including mitochondrial disorders and certain types of cancer.
By targeting the HCCS protein, researchers can gain insight into its function and potential therapeutic implications.This polyclonal antibody detects HCCS protein in a variety of cell types, making it a versatile tool for studies in cell biology, biochemistry, and mitochondrial research. Its high specificity and sensitivity make it ideal for investigating the role of HCCS in health and disease, paving the way for new insights and potential treatment strategies.
Product Name:
HCCS Rabbit Polyclonal Antibody
SKU:
CAB7490
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-268 of human HCCS (NP_005324.3).
The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3052
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HCCS antibody (CAB7490) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
