The HBZ Polyclonal Antibody (CAB6920) is a valuable tool for researchers studying the HTLV-1 viral protein HBZ and its role in viral persistence and pathogenesis. This polyclonal antibody, raised in rabbits, has been validated for use in various applications, including Western blot, immunofluorescence, and immunoprecipitation.HBZ is a key protein encoded by the HTLV-1 virus that plays a crucial role in the virus' ability to evade the host immune system and establish persistent infection.
By targeting HBZ with this antibody, researchers can gain insight into the molecular mechanisms underlying HTLV-1 pathogenesis, as well as identify potential therapeutic targets for HTLV-1-associated diseases.With its high reactivity with human samples and specificity for HBZ, the CAB6920 antibody is an essential tool for any researcher investigating the molecular biology of HTLV-1 and seeking to develop new strategies for the treatment of HTLV-1-related disorders.
Product Name:
HBZ Rabbit Polyclonal Antibody
SKU:
CAB6920
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human HBZ (NP_005323.1).
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'.
Purification Method:
Affinity purification
Gene ID:
3050
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of K-562 cells, using HBZ Antibody (CAB6920) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.