HBV AG-2 Monoclonal Antibody [NYRHepB-2] (CPAB0377)
- SKU:
- CPAB0377
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Virus
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- NYRHepB-2
- Applications:
- IP
- WB
- ELISA
- IHC
Description
HBV AG-2 Monoclonal Antibody [NYRHepB-2] (CPAB0377)
The HBV Ag-2 Antibody (CPAB0377) is a high-quality monoclonal antibody specifically designed for research on Hepatitis B Virus (HBV) surface antigen 2. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in a variety of research applications, including ELISA and immunohistochemistry.HBV Ag-2 is a critical marker for the detection and diagnosis of Hepatitis B infection, making this antibody an essential tool for studying the virus and its interactions with the host immune system. By targeting HBV Ag-2, researchers can gain valuable insights into the pathogenesis of HBV infection, as well as potential therapeutic targets for the development of new treatments to combat this widespread disease.
With its high specificity and sensitivity, the HBV Ag-2 Antibody is a valuable resource for researchers in the fields of virology, immunology, and infectious diseases. Its ability to detect and quantify HBV Ag-2 in various sample types makes it an ideal choice for studies aiming to better understand the biology of HBV and improve diagnostic methods for Hepatitis B.
Product Name: | HBV AG-2 antibody |
Product Sku: | CPAB0377 |
Size: | 500μg |
Host Species: | mouse |
Immunogen: | r.Hep B vaccine (BTG) |
Clone: | NYRHepB-2. |
Reactivity: | Viral |
Applications: | Immuneprecipitation, Western Blot, ELISA, Immunohistochemistry |
Purification Method: | Ion exchange column. |
Isotype: | IgG1 |
Background: | Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA. |
Synonyms: | |
Storage Buffer: | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |