HBP1 Transcription Factor Activity Assay
- SKU:
- TFAB00192
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- HBP1
- Reactivity:
- Human
- Mouse
- Rat
Description
HBP1 Transcription Factor Activity Assay
The HBP1 Transcription Factor Activity Assay is a highly sensitive and specific kit designed for the detection of HBP1 transcription factor activity in various biological samples. This assay provides accurate and reproducible results, making it an essential tool for researchers studying gene regulation and transcriptional activity.HBP1 is a key transcription factor that plays a crucial role in regulating gene expression, cell proliferation, and differentiation. Dysregulation of HBP1 activity has been linked to various diseases, including cancer, diabetes, and autoimmune disorders.
Therefore, studying HBP1 transcription factor activity can provide valuable insights into disease mechanisms and potential therapeutic strategies.With its user-friendly protocol and reliable performance, the HBP1 Transcription Factor Activity Assay is suitable for a wide range of research applications, including drug discovery, biomarker identification, and basic research. Invest in this assay to advance your studies in gene regulation and transcriptional control.
| Product Name: | HBP1 Transcription Factor Activity Assay |
| Product Code: | TFAB00192 |
| Target: | HBP1 |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie HBP1 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | HBP1: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 7q22.3 Cellular Component: nucleoplasm Molecular Function:protein binding; DNA binding; RNA binding Biological Process: Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of potassium ion transport; cell cycle arrest |
| UniProt Code: | O60381 |
| NCBI GenInfo Identifier: | 346716352 |
| NCBI Gene ID: | 26959 |
| NCBI Accession: | NP_001231191.1 |
| UniProt Secondary Accession: | O60381,Q8TBM1, Q8TE93, Q96AJ2, B3KVB7, |
| UniProt Related Accession: | O60381 |
| Molecular Weight: | 57,645 Da |
| NCBI Full Name: | HMG box-containing protein 1 isoform 1 |
| NCBI Synonym Full Names: | HMG-box transcription factor 1 |
| NCBI Official Symbol: | HBP1Â Â |
| NCBI Protein Information: | HMG box-containing protein 1; HMG box transcription factor 1; high mobility group box transcription factor 1 |
| UniProt Protein Name: | HMG box-containing protein 1 |
| UniProt Synonym Protein Names: | HMG box transcription factor 1; High mobility group box transcription factor 1 |
| Protein Family: | HMG box-containing protein |
| UniProt Gene Name: | HBP1Â Â |
| UniProt Entry Name: | HBP1_HUMAN |
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