The Hbegf Polyclonal Antibody (CAB1695) is a valuable tool for research involving the HBEGF protein, a member of the epidermal growth factor family known for its role in cell proliferation, differentiation, and migration. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it suitable for a variety of applications, including Western blot and immunohistochemistry.HBEGF, also known as heparin-binding EGF-like growth factor, is a key player in numerous biological processes, including wound healing, tissue regeneration, and tumorigenesis.
Its involvement in these pathways makes it a promising target for studying various diseases, such as cancer, cardiovascular disorders, and developmental abnormalities. By using the HBEGF Polyclonal Antibody, researchers can explore the expression and function of HBEGF in different cell types and tissues, gaining valuable insights into its potential therapeutic applications.
Product Name:
HB-EGF Rabbit Polyclonal Antibody
SKU:
CAB1695
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human HB-EGF (NP_001936.1).
Cell membrane, Secreted, Single-pass type I membrane protein, extracellular space.
Calculated MW:
23kDa
Observed MW:
23kDa
Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis.
Purification Method:
Affinity purification
Gene ID:
1839
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat kidney, using HB-EGF antibody (CAB1695) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
