The HBE1 Polyclonal Antibody (CAB3909) is a valuable tool for researchers studying the HBE1 protein, which is involved in airway defense and immune response. This antibody is raised in rabbits and is highly specific to human samples, making it ideal for use in various research applications, including Western blotting.HBE1, also known as human beta defensin 1, is a key component of the host defense system in the respiratory tract, playing a crucial role in protecting against infections. By targeting the HBE1 protein, researchers can analyze its expression levels and localization in different cell types, providing insight into its function in immune defense mechanisms.
Understanding the role of HBE1 in immune response modulation can have important implications for research into respiratory infections, inflammatory conditions, and other diseases affecting the respiratory system. The HBE1 Polyclonal Antibody offers a reliable tool for investigating the function and regulation of this important protein, advancing our knowledge in the field of immunology and respiratory biology.
Product Name:
HBE1 Rabbit Polyclonal Antibody
SKU:
CAB3909
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human HBE1 (NP_005321.1).
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'
Purification Method:
Affinity purification
Gene ID:
3046
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of K-562 cells, using HBE1 antibody (CAB3909) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
