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HBB Rabbit Polyclonal Antibody (CAB1331)

SKU:
CAB1331
Product Type:
Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:HBB Rabbit Polyclonal Antibody
SKU:CAB1331
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 47-147 of human HBB (NP_000509.1).
Sequence:GDLS TPDA VMGN PKVK AHGK KVLG AFSD GLAH LDNL KGTF ATLS ELHC DKLH VDPE NFRL LGNV LVCV LAHH FGKE FTPP VQAA YQKV VAGV ANAL AHKY H
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:ECYT6; CD113t-C; beta-globin; HBB
Positive Sample:Raji
Conjugate:Unconjugated
Cellular Localization:blood microparticle, cytosol, extracellular exosome, extracellular region, extracellular space, hemoglobin complex
Calculated MW:16kDa
Observed MW:16kDa

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Purification Method:Affinity purification
Gene ID:3043
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of Raji cells, using HBB antibody (CAB1331) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.

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