Hemoglobin subunit alpha (HBA1) Rabbit Polyclonal Antibody (CAB7322)
- SKU:
- CAB7322
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | Hemoglobin subunit alpha (HBA1) Rabbit Polyclonal Antibody |
SKU: | CAB7322 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human Hemoglobin subunit alpha (Hemoglobin subunit alpha (HBA1)) (NP_000508.1). |
Sequence: | MVLS PADK TNVK AAWG KVGA HAGE YGAE ALER MFLS FPTT KTYF PHFD LSHG SAQV KGHG KKVA DALT NAVA HVDD MPNA LSAL SDLH AHKL RVDP VNFK LLSH CLLV TLAA HLPA EFTP AVHA SLDK FLAS VSTV LTSK YR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HBH; ECYT7; HBA-T3; METHBA; Hemoglobin subunit alpha (HBA1) |
Positive Sample: | MCF7,Mouse liver,Mouse blood cells,Rat liver,Rat blood cells |
Conjugate: | Unconjugated |
Cellular Localization: | blood microparticle, cytosol, extracellular exosome, extracellular region, extracellular space, hemoglobin complex |
Calculated MW: | 15kDa |
Observed MW: | 14kDa/25kDa |
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Purification Method: | Affinity purification |
Gene ID: | 3039 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |