HAX1 Rabbit Polyclonal Antibody (CAB5551)
- SKU:
- CAB5551
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | HAX1 Rabbit Polyclonal Antibody |
SKU: | CAB5551 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-279 of human HAX1 (NP_006109.2). |
Sequence: | MSLF DLFR GFFG FPGP RSHR DPFF GGMT RDED DDEE EEEE GGSW GRGN PRFH SPQH PPEE FGFG FSFS PGGG IRFH DNFG FDDL VRDF NSIF SDMG AWTL PSHP PELP GPES ETPG ERLR EGQT LRDS MLKY PDSH QPRI FGGV LESD ARSE SPQP APDW GSQR PFHR FDDV WPMD PHPR TRED NDLD SQVS QEGL GPVL QPQP KSYF KSIS VTKI TKPD GIVE ERRT VVDS EGRT ETTV TRHE ADSS PRGD PESP RPPA LDDA FSIL DLFL GRWF RSR |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:10 - 1:100 |
Synonyms: | SCN3; HS1BP1; HCLSBP1; HAX1 |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic vesicle, Endoplasmic reticulum, Mitochondrion, Nucleus membrane, Sarcoplasmic reticulum. |
Calculated MW: | 32kDa |
Observed MW: | 35kDa |
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10456 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |