The HAVCR1 Polyclonal Antibody (CAB2831) is a vital tool for researchers studying the HAVCR1 protein, also known as TIM-1, an essential cell surface molecule involved in immune responses and allergic reactions. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications, enabling precise detection and analysis of HAVCR1 in various cell types.HAVCR1/TIM-1 is a key regulator of immune responses, playing a crucial role in immune tolerance and autoimmune diseases.
Its involvement in allergic reactions and asthma makes it a promising target for therapeutic interventions aimed at modulating immune function in these conditions. By understanding the role of HAVCR1, researchers can develop innovative treatments for diseases such as asthma, allergies, and autoimmune disorders.
Product Name:
HAVCR1 Rabbit Polyclonal Antibody
SKU:
CAB2831
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-125 of human HAVCR1 (NP_036338.2).
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. The protein is a receptor for multiple other viruses, including Ebola virus, Marburg virus, Dengue virus, and Zika virus and is a possible entry factor for SARS-CoV-2 and other coronaviruses.
Purification Method:
Affinity purification
Gene ID:
26762
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HAVCR1 antibody (CAB2831) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
