USP7/HAUSP Rabbit Monoclonal Antibody (CAB3448)
- SKU:
- CAB3448
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | USP7/HAUSP Rabbit Monoclonal Antibody |
SKU: | CAB3448 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human USP7/HAUSP (Q93009). |
Sequence: | MVMP RFYP DRPH QKSV GFFL QCNA ESDS TSWS CHAQ AVLK IINY RDDE KSFS RRIS HLFF HKEN DWGF SNFM AWSE VTDP EKGF IDDD KVTF EVFV QADA P |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | TEF1; HAUSP; HAFOUS; DEL16P13.2; C16DELp13.2; USP7/HAUSP |
Positive Sample: | HeLa,MCF7,PC-3,Mouse testis,Mouse brain,Rat testis,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, PML body. |
Calculated MW: | 128kDa |
Observed MW: | 140kDa |
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
Purification Method: | Affinity purification |
Gene ID: | 7874 |
Clone Number: | ARC0777 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |