The HAUS4 Antibody (PACO43692) is a high-quality polyclonal antibody designed for researchers studying the HAUS4 protein. HAUS4 is a component of the Augmin complex, which plays a critical role in microtubule generation during cell division. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.By binding to the HAUS4 protein, this antibody enables the detection and analysis of HAUS4 in various cell types. This makes it a valuable tool for research in cell biology, cancer biology, and developmental biology.
Understanding the function of HAUS4 and its role in microtubule generation is essential for advancing our knowledge of cell division processes and potentially identifying new therapeutic targets for cancer treatment.Overall, the HAUS4 Antibody (PACO43692) offers researchers a reliable and effective tool for studying the function of HAUS4 and its involvement in cellular processes. Its high specificity and reactivity make it a valuable addition to any laboratory conducting research in the field of cell biology and cancer biology.
Recombinant Human HAUS augmin-like complex subunit 4 protein (1-363AA)
Form:
Liquid
Storage Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method:
Antigen Affinity Purified
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot. All lanes: HAUS augmin-like complex subunit 4 antibody at 6µg/ml + Rat brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 43, 28, 29, 38 kDa. Observed band size: 43 kDa.
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43692 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human skin tissue using PACO43692 at dilution of 1:100.
Background:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Synonyms:
HAUS augmin-like complex subunit 4, HAUS4, C14orf94
UniProt Protein Function:
HAUS4: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Belongs to the HAUS4 family. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 14q11.2Cellular Component: centrosome; microtubule; cytoplasm; spindleBiological Process: mitosis; centrosome organization and biogenesis; cell division; spindle assembly
UniProt Protein Details:
NCBI Summary:
This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
