The HAUS4 Antibody (PAC043691) is a highly specific polyclonal antibody designed for research involving the HAUS4 protein. HAUS4 is a key component of the Augmin complex, which plays a critical role in microtubule generation and spindle assembly during cell division. This antibody is raised in rabbits and is validated for use in a variety of research applications, including Western blot and immunofluorescence.The HAUS4 Antibody binds specifically to the HAUS4 protein, allowing for precise detection and analysis in various cell types.
Its high reactivity with human samples makes it ideal for studies in biology, cell division, and cancer research. Understanding the function and regulation of HAUS4 is essential for unraveling the mechanisms underlying cell division and potential therapeutic targets for cancer treatment.Researchers can rely on the HAUS4 Antibody (PAC043691) to provide accurate and reliable results in their studies, making it a valuable tool for advancing our understanding of cell division and its implications in disease progression.
Antibody Name:
HAUS4 Antibody (PACO43691)
Antibody SKU:
PACO43691
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human HAUS augmin-like complex subunit 4 protein (1-363AA)
Form:
Liquid
Storage Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method:
Antigen Affinity Purified
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemistry of paraffin-embedded human skin tissue using PACO43691 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43691 at dilution of 1:100.
Background:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Synonyms:
HAUS augmin-like complex subunit 4, HAUS4, C14orf94
UniProt Protein Function:
HAUS4: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Belongs to the HAUS4 family. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 14q11.2Cellular Component: centrosome; microtubule; cytoplasm; spindleBiological Process: mitosis; centrosome organization and biogenesis; cell division; spindle assembly
UniProt Protein Details:
NCBI Summary:
This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
