The HAUS4 Antibody (PACO08080) is a polyclonal antibody designed for research involving the HAUS4 protein, which is essential for centrosome integrity and mitotic spindle assembly. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including immunofluorescence and immunocytochemistry.HAUS4 plays a crucial role in cell division and proper chromosome segregation, making it a key target for studies in cell biology and cancer research.
Understanding the function and regulation of HAUS4 is important for uncovering mechanisms of tumorigenesis and identifying potential therapeutic targets for cancer treatment.Overall, the HAUS4 Antibody provides researchers with a valuable tool for investigating the role of HAUS4 in cellular processes and disease progression, ultimately advancing our understanding of molecular biology and offering potential insights for the development of novel cancer therapies.
chromosome 14 open reading frame 94;C14orf94;FLJ20424 ;
UniProt Protein Function:
HAUS4: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Belongs to the HAUS4 family. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 14q11.2Cellular Component: centrosome; microtubule; cytoplasm; spindleBiological Process: mitosis; centrosome organization and biogenesis; cell division; spindle assembly
UniProt Protein Details:
NCBI Summary:
This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
