KAT1/HAT1 Rabbit Monoclonal Antibody (CAB4423)
- SKU:
- CAB4423
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | KAT1/HAT1 Rabbit Monoclonal Antibody |
SKU: | CAB4423 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human KAT1/HAT1 (NP_003633.2). |
Sequence: | HYFL VFEK YNKD GATL FATV GYMT VYNY YVYP DKTR PRVS QMLI LTPF QGQG HGAQ LLET VHRY YTEF PTVL DITA EDPS KSYV KLRD FVLV KLCQ DLPC FSRE KLMQ GFNE DMVI EAQQ KFKI NKQH ARRV YEIL RLLV TDMS DAEQ YRSY RLDI KRRL ISPY KKKQ RDLA KMRK CLRP EELT NQMN QIEI SMQH EQLE E |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | KAT1; KAT1/HAT1 |
Positive Sample: | MCF7,U-87MG,Mouse testis,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, Nucleus matrix, nucleoplasm. |
Calculated MW: | 50kDa |
Observed MW: | 49kDa |
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8520 |
Clone Number: | ARC1002 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |