The HAS3 Polyclonal Antibody (CAB6617) is a versatile tool for researchers studying the HA synthases family, specifically HAS3, an enzyme responsible for the synthesis of hyaluronan, a key component of the extracellular matrix. This antibody, raised in rabbits, exhibits high reactivity with human samples and is suitable for use in various applications, including Western blot and immunohistochemistry.HAS3 has been implicated in various physiological and pathological processes, including tissue regeneration, inflammation, and cancer progression.
By targeting HAS3 with this antibody, researchers can investigate its role in these processes and potentially identify therapeutic targets for diseases where hyaluronan dysregulation is observed.Overall, the HAS3 Polyclonal Antibody offers researchers a reliable tool for studying the function of HAS3 in various biological contexts, with the potential to advance our understanding of hyaluronan biology and its implications in health and disease.
Product Name:
HAS3 Rabbit Polyclonal Antibody
SKU:
CAB6617
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 67-281 of human HAS3 (NP_619515.1).
The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3038
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HAS3 antibody (CAB6617) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
