The HAS3 Polyclonal Antibody (CAB13498) is a valuable tool for research involving HAS3, an important enzyme responsible for the synthesis of hyaluronan, a key component of the extracellular matrix. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for various experimental techniques, including Western blotting.HAS3, also known as hyaluronan synthase 3, plays a crucial role in maintaining tissue hydration and structural integrity, making it essential for processes such as wound healing, tissue repair, and inflammation. Dysregulation of HAS3 expression has been implicated in various pathological conditions, including cancer metastasis, fibrosis, and inflammatory diseases.
Therefore, studying the function and regulation of HAS3 can provide valuable insights into these disease processes and potentially lead to the development of novel therapeutic strategies.By utilizing the HAS3 Polyclonal Antibody (CAB13498) in your research, you can effectively investigate the expression levels and localization of HAS3 in different cell types and tissues, furthering our understanding of its physiological functions and pathological roles. This antibody offers a reliable and specific tool for immunodetection assays, enhancing the accuracy and reliability of your experimental results in the fields of cell biology, biochemistry, and medical research.
Product Name:
HAS3 Rabbit Polyclonal Antibody
SKU:
CAB13498
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 67-281 of human HAS3 (NP_619515.1).
The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3038
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HAS3 antibody (CAB13498) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
