HARS2 Rabbit Polyclonal Antibody (CAB7785)
- SKU:
- CAB7785
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | HARS2 Rabbit Polyclonal Antibody |
SKU: | CAB7785 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 217-506 of human HARS2 (NP_036340.1). |
Sequence: | IVDG MFAV CGVP ESKF RAIC SSID KLDK MAWK DVRH EMVV KKGL APEV ADRI GDYV QCHG GVSL VEQM FQDP RLSQ NKQA LEGL GDLK LLFE YLTL FGIA DKIS FDLS LARG LDYY TGVI YEAV LLQT PTQA GEEP LNVG SVAA GGRY DGLV GMFD PKGH KVPC VGLS IGVE RIFY IVEQ RMKT KGEK VRTT ETQV FVAT PQKN FLQE RLKL IAEL WDSG IKAE MLYK NNPK LLTQ LHYC ESTG IPLV VIIG EQEL KEGV IKIR SVAS REEV AIKR ENFV AEIQ KRLS ES |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HO3; HARSL; HARSR; HisRS; PRLTS2; HARS2 |
Positive Sample: | U-251MG,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 57kDa |
Observed MW: | 50kDa |
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.
Purification Method: | Affinity purification |
Gene ID: | 23438 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |