HARS Rabbit Polyclonal Antibody (CAB7899)
- SKU:
- CAB7899
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | HARS Rabbit Polyclonal Antibody |
SKU: | CAB7899 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HARS (NP_002100.2). |
Sequence: | MAER AALE ELVK LQGE RVRG LKQQ KASA ELIE EEVA KLLK LKAQ LGPD ESKQ KFVL KTPK GTRD YSPR QMAV REKV FDVI IRCF KRHG AEVI DTPV FELK ETLM GKYG EDSK LIYD LKDQ GGEL LSLR YDLT VPFA RYLA MNKL TNIK RYHI AKVY RRDN PAMT RGRY REFY QCDF DIAG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HRS; HARS; CMT2W; USH3B |
Positive Sample: | MCF7,HeLa,U-251MG,NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3035 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |