The HAPLN1 Polyclonal Antibody (CAB12429) is a valuable tool for researchers studying HAPLN1, a key protein involved in the regulation of extracellular matrix stability and cell adhesion. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the HAPLN1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it particularly useful for studies in cell biology and tissue engineering.HAPLN1, also known as hyaluronan and proteoglycan link protein 1, plays an essential role in maintaining the structure and function of connective tissues by binding to hyaluronic acid and proteoglycans.
Dysregulation of HAPLN1 has been associated with various pathological conditions, including osteoarthritis and cancer metastasis. Investigating the function of HAPLN1 is crucial for understanding these diseases and developing targeted therapeutic interventions.Overall, the HAPLN1 Polyclonal Antibody (CAB12429) is a reliable tool for researchers seeking to explore the role of HAPLN1 in health and disease. Its high specificity and sensitivity make it an essential component of any study involving this important protein.
Product Name:
HAPLN1 Rabbit Polyclonal Antibody
SKU:
CAB12429
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 165-354 of human HAPLN1 (NP_001875.1).
Predicted to enable hyaluronic acid binding activity. Predicted to be an extracellular matrix structural constituent conferring compression resistance. Predicted to be involved in central nervous system development and skeletal system development. Colocalizes with collagen-containing extracellular matrix.
Purification Method:
Affinity purification
Gene ID:
1404
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using HAPLN1 Rabbit pAb (CAB12429) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
