HADHB Rabbit Polyclonal Antibody (CAB5716)
- SKU:
- CAB5716
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
Product Name: | HADHB Rabbit Polyclonal Antibody |
SKU: | CAB5716 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 34-270 of human HADHB (NP_000174.1). |
Sequence: | AAPA VQTK TKKT LAKP NIRN VVVV DGVR TPFL LSGT SYKD LMPH DLAR AALT GLLH RTSV PKEV VDYI IFGT VIQE VKTS NVAR EAAL GAGF SDKT PAHT VTMA CISA NQAM TTGV GLIA SGQC DVIV AGGV ELMS DVPI RHSR KMRK LMLD LNKA KSMG QRLS LISK FRFN FLAP ELPA VSEF STSE TMGH SADR LAAA FAVS RLEQ DEYA LRSH SLAK KAQD EGLL SDVV PFKV P |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:10 - 1:100 |
Synonyms: | ECHB; MTPB; MTPD; MTPD2; MSTP029; TP-BETA; HADHB |
Positive Sample: | HeLa,Mouse heart,293F,NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum, Mitochondrion, Mitochondrion inner membrane, Mitochondrion outer membrane. |
Calculated MW: | 51kDa |
Observed MW: | 51kDa/ |
This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 3032 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |