HA Antibody (PACO50462)
- SKU:
- PACO50462
- Product Type:
- Antibody
- Reactivity:
- Virus - Influenza A
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | HA Antibody (PACO50462) |
| Antibody SKU: | PACO50462 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Influenza A virus |
| Immunogen: | Recombinant Influenza A virus Hemagglutinin protein (18-343AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in Recombinant protein. All lanes: HA antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. predicted band size: 64 kDa. observed band size: 64 kDa.. |
| Background: | Binds to sialic acid, containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore (By similarity). |
| Synonyms: | Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain], HA |
| UniProt Protein Function: | Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q0HD60 |
| NCBI GenInfo Identifier: | 123859819 |
| NCBI Gene ID: | |
| NCBI Accession: | Q0HD60.1 |
| UniProt Secondary Accession: | Q0HD60 |
| UniProt Related Accession: | Q0HD60 |
| Molecular Weight: | 52.6 kDa |
| NCBI Full Name: | Hemagglutinin |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Hemagglutinin |
| UniProt Synonym Protein Names: | |
| Protein Family: | Hemagglutinin |
| UniProt Gene Name: | HAÂ Â |
| UniProt Entry Name: | HEMA_I40A0 |