The HA Antibody (PAC050462) offered by AssayGenie is a high-quality polyclonal antibody designed for research involving the HA protein. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting.HA, also known as human albumin, is a critical protein found in the blood that plays a key role in maintaining osmotic pressure and transporting essential molecules throughout the body. Research into HA is important for understanding its functions in health and disease, particularly in conditions such as liver disease, kidney disease, and cardiovascular disorders.
By utilizing the HA Antibody from AssayGenie, researchers can accurately detect and analyze HA protein levels in different cell types, aiding in studies related to physiology, pathology, and therapeutic development. This antibody is a valuable tool for investigating the role of HA in various biological processes and diseases, providing crucial insights for advancing medical research and improving patient care.
Antibody Name:
HA Antibody (PACO50462)
Antibody SKU:
PACO50462
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Influenza A virus
Immunogen:
Recombinant Influenza A virus Hemagglutinin protein (18-343AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: HA antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. predicted band size: 64 kDa. observed band size: 64 kDa..
Background:
Binds to sialic acid, containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore (By similarity).
Synonyms:
Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain], HA
UniProt Protein Function:
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore ().
