The H2-K1 Monoclonal Antibody (PACO34626) is an essential tool for research involving the H2-K1 protein, a key component in the major histocompatibility complex (MHC) class I pathway. This antibody, produced through hybridoma technology, is highly specific to human samples and has been validated for use in various applications, including flow cytometry and immunohistochemistry.H2-K1 is crucial for presenting antigenic peptides to cytotoxic T cells, playing a critical role in immune surveillance and response. Studies involving H2-K1 are essential for understanding the adaptive immune system and its role in immune defense against pathogens and tumors.
The H2-K1 Monoclonal Antibody enables precise detection and analysis of H2-K1 expression in different cell types, making it a valuable tool for research in immunology, infectious diseases, and cancer immunotherapy.Researchers studying immune response, antigen presentation, and T cell activation will benefit from the specificity and reliability of the H2-K1 Monoclonal Antibody (PACO34626) in their experiments. Its application in diverse research areas makes it a versatile reagent for investigations into the complex mechanisms of the immune system.
Antibody Name:
H2-K1 Antibody (PACO34626)
Antibody SKU:
PACO34626
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Mouse
Immunogen:
Recombinant Mouse H-2 class I histocompatibility antigen, K-D α chain protein (22-305AA)
H-2 class I histocompatibility antigen, K-D α chain (H-2K(D)), H2-K1, H2-K
UniProt Protein Function:
H2-K1(D): Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 17 B1|17 17.98 cMCellular Component: cell surface; endoplasmic reticulum; external side of plasma membrane; Golgi apparatus; Golgi medial cisterna; membrane; MHC class I protein complexMolecular Function: beta-2-microglobulin binding; peptide antigen binding; peptide binding; protein binding; protein heterodimerization activity; receptor binding; RNA binding; T cell receptor binding; TAP bindingBiological Process: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; antigen processing and presentation of exogenous peptide antigen via MHC class I; defense response to bacterium; inner ear development; positive regulation of T cell mediated cytotoxicity