The H2-D1 Monoclonal Antibody (PACO34946) is a valuable tool for researchers studying immune responses and antigen presentation. This antibody, developed for use in various research applications, specifically targets the H2-D1 protein, a major histocompatibility complex (MHC) class I molecule involved in presenting antigens to T cells.The high specificity and sensitivity of this antibody make it an excellent choice for studies investigating the role of H2-D1 in immune surveillance, autoimmune diseases, and anti-tumor immunity. By detecting and analyzing H2-D1 expression in different cell types, researchers can gain insights into the mechanisms of immune recognition and response, paving the way for the development of novel immunotherapies and vaccines.
The H2-D1 Monoclonal Antibody (PACO34946) offers reliable results in Western blot, immunofluorescence, and flow cytometry experiments, providing valuable information for advancing our understanding of immune function and disease pathogenesis. With its versatility and robust performance, this antibody is an essential tool for researchers in immunology, oncology, and vaccine development.
Antibody Name:
H2-D1 Antibody (PACO34946)
Antibody SKU:
PACO34946
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Mouse, Human
Immunogen:
Recombinant Mouse H-2 class I histocompatibility antigen, D-D α chain protein (25-311AA)
Western blot. All lanes: H2-D1 antibody at 2µg/ml + A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 42 kDa. Observed band size: 42 kDa.
Background:
Involved in the presentation of foreign antigens to the immune system.
Synonyms:
H-2 class I histocompatibility antigen, D-D α chain (H-2D(D)), H2-D1
UniProt Protein Function:
H2-D1(D): Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 17 B1|17 18.61 cMCellular Component: cell surface; endoplasmic reticulum; external side of plasma membrane; Golgi apparatus; Golgi medial cisterna; lipid raft; membrane; MHC class I protein complex; plasma membraneMolecular Function: beta-2-microglobulin binding; peptide antigen binding; peptide binding; protein binding; protein heterodimerization activity; receptor binding; RNA binding; T cell receptor binding; TAP bindingBiological Process: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; positive regulation of T cell mediated cytotoxicity
