The H2-AB1 Polyclonal Antibody (CAB18658) is a valuable tool for researchers studying the H2-AB1 protein, a member of the major histocompatibility complex (MHC) class II molecules. This rabbit polyclonal antibody is highly specific and reactive with human samples, making it ideal for use in a variety of research applications, particularly in immunology and disease studies.H2-AB1 plays a crucial role in antigen presentation and immune response regulation, making it a key target for investigation in diseases like cancer, autoimmune disorders, and infectious diseases.
By using this antibody in studies such as Western blotting and immunohistochemistry, researchers can accurately detect and analyze H2-AB1 expression in various cell types, helping to deepen our understanding of its function and potential therapeutic implications.With its high specificity, reliability, and versatility, the H2-AB1 Polyclonal Antibody (CAB18658) is a valuable tool for researchers looking to explore the role of the H2-AB1 protein in immune system function and disease pathology.
Product Name:
H2-Ab1 Rabbit Polyclonal Antibody
SKU:
CAB18658
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-219 of mouse H2-Ab1 (NP_996988.2).
cell surface, early endosome, external side of plasma membrane, Golgi apparatus, multivesicular body, plasma membrane
Calculated MW:
30kDa
Observed MW:
30kDa
Enables several functions, including peptide antigen binding activity; protein antigen binding activity; and toxic substance binding activity. Involved in several processes, including B cell affinity maturation; cellular response to interferon-gamma; and positive regulation of T-helper 1 type immune response. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and immune response. Located in Golgi apparatus; endosome; and external side of plasma membrane. Is integral component of membrane. Part of MHC class II protein complex. Is expressed in lung; metanephros; and thymus primordium. Orthologous to human HLA-DQB2 (major histocompatibility complex, class II, DQ beta 2).
Purification Method:
Affinity purification
Gene ID:
14961
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse large intestine, using H2-Ab1 Rabbit pAb (CAB18658) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
