H2-Aa Rabbit Polyclonal Antibody (CAB18325)
- SKU:
- CAB18325
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | H2-Aa Rabbit Polyclonal Antibody |
SKU: | CAB18325 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-208 of mouse H2-Aa (NP_034508.2). |
Sequence: | IEAD HVGT YGIS VYQS PGDI GQYT FEFD GDEL FYVD LDKK ETVW MLPE FGQL ASFD PQGG LQNI AVVK HNLG VLTK RSNS TPAT NEAP QATV FPKS PVLL GQPN TLIC FVDN IFPP VINI TWLR NSKS VADG VYET SFFV NRDY SFHK LSYL TFIP SDDD IYDC KVEH WGLE EPVL KHWE PE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | Ia1; H2Aa; Ia-1; H-2Aa; Aalpha; IAalpha; I-Aalpha; H2-Aa |
Positive Sample: | Mouse lung,Mouse kidney |
Cellular Localization: | external side of plasma membrane, lysosome, plasma membrane |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
Enables peptide antigen binding activity. Involved in response to interferon-gamma. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and positive regulation of T cell differentiation. Located in external side of plasma membrane and lysosome. Part of MHC class II protein complex. Is expressed in central nervous system; retina; and thymus primordium. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); glomerulonephritis (multiple); hematologic cancer (multiple); and systemic scleroderma (multiple). Orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1).
Purification Method: | Affinity purification |
Gene ID: | 14960 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |