The GYS2 Polyclonal Antibody (CAB13020) is a valuable tool for researchers studying the glycogen synthase 2 (GYS2) protein, involved in regulating glycogen synthesis in the body. This antibody, raised in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to the GYS2 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential resource for research in metabolism, diabetes, and glycogen storage disorders.GYS2 plays a crucial role in maintaining glucose homeostasis by controlling the synthesis of glycogen, the body's main storage form of glucose.
Dysregulation of GYS2 has been linked to various metabolic disorders, including diabetes and glycogen storage diseases, highlighting its importance in overall metabolic health. Studying the function of GYS2 with the help of this antibody can provide valuable insights into metabolic pathways and potential therapeutic targets for metabolic diseases.Overall, the GYS2 Polyclonal Antibody is a reliable tool for researchers investigating the role of GYS2 in metabolic processes, offering a means to accurately study and understand its function in health and disease.
Product Name:
GYS2 Rabbit Polyclonal Antibody
SKU:
CAB13020
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 594-703 of human GYS2 (NP_068776.2).
The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content.
Purification Method:
Affinity purification
Gene ID:
2998
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse liver, using GYS2 Rabbit pAb (CAB13020) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
