The GYS1 Rabbit Monoclonal Antibody (CAB8912) is a cutting-edge tool for research involving GYS1, a key enzyme involved in glycogen synthesis. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity for GYS1 in human samples, making it an ideal choice for Western blot applications. By binding to the GYS1 protein, this antibody enables precise detection and analysis in various cell types, facilitating studies in metabolic pathways, glycogen metabolism, and related research areas.
GYS1, also known as glycogen synthase, is a critical regulator of glycogen storage and energy metabolism in cells. Dysregulation of GYS1 has been implicated in a variety of metabolic disorders, making it a promising target for therapeutic interventions in conditions such as diabetes, obesity, and metabolic syndrome. By elucidating the role of GYS1 in cellular processes, researchers can gain valuable insights into metabolic pathways and develop novel strategies for managing metabolic disorders effectively.
The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2997
Clone Number:
ARC1350
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Glycogen synthase 1 (Glycogen synthase 1 (GYS1)) Rabbit mAb (CAB8912) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
