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GYPA Monoclonal Antibody [NYRhGlycophorinA] (CPAB0493)

SKU:
CPAB0493
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
NYRhGlycophorinA
Applications:
WB
FC
€660
Frequently bought together:

Description

system_update_alt Datasheet

GYPA Monoclonal Antibody [NYRhGlycophorinA] (CPAB0493)

The GYPA Polyclonal Antibody (CPAB0493) is a valuable tool for researchers studying the glycophorin A protein, a key component of the red blood cell membrane. This antibody is generated in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications for protein detection and analysis.Glycophorin A is essential for maintaining the structural integrity of red blood cells and plays a crucial role in cell adhesion and signaling. Studies have implicated glycophorin A in various physiological and pathological processes, including blood group antigen recognition and malaria parasite invasion.

By targeting this protein with the GYPA Polyclonal Antibody, researchers can gain insights into its function and potential roles in disease development.This antibody is an invaluable tool for investigations in hematology, immunology, and other fields where the role of glycophorin A is of interest. With its specificity and reliability, the GYPA Polyclonal Antibody is a valuable asset for researchers seeking to expand their understanding of red blood cell biology and related disorders.

Product Name:GYPA Antibody
Product Sku:CPAB0493
Size:500μg
Host Species:Mouse
Immunogen:r.Human GlycophorinA
Clone:NYRhGlycophorinA.
Reactivity:Other bodies
Applications:Western Blot, Flow Cytometry
Purification Method:Protein A column.
Isotype:IgG1
Background:Glycophorins A & B (GYPA &GYPB) are the main sialoglycoproteins of the human erythrocyte membrane which carry the antigenic determinants for the MN and Ss blood groups. Along with the M or N and S or s antigens which normally occur in all populations, approximately 40 related variant phenotypes were identified. These variants comprise all the variants of the Miltenberger complex and some isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. GYPA is significant for the function of SLC4A1 and is necessary for high activity of SLC4A1. GYPA is involved in translocation of SLC4A1 to the plasma membrane. GYPA is also a receptor for: the influenza virus, Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175), binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans and is also a receptor for Hepatitis A virus (HAV).
Synonyms:Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GPA, MN, MNS, GPSAT, GPErik, HGpMiV, HGpMiXI, HGpSta(C).
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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