GUCY2D Rabbit Polyclonal Antibody (CAB3605)
- SKU:
- CAB3605
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | GUCY2D Rabbit Polyclonal Antibody |
SKU: | CAB3605 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 52-350 of human GUCY2D (NP_000171.1). |
Sequence: | AVFT VGVL GPWA CDPI FSRA RPDL AARL AAAR LNRD PGLA GGPR FEVA LLPE PCRT PGSL GAVS SALA RVSG LVGP VNPA ACRP AELL AEEA GIAL VPWG CPWT QAEG TTAP AVTP AADA LYAL LRAF GWAR VALV TAPQ DLWV EAGR SLST ALRA RGLP VASV TSME PLDL SGAR EALR KVRD GPRV TAVI MVMH SVLL GGEE QRYL LEAA EELG LTDG SLVF LPFD TIHY ALSP GPEA LAAL ANSS QLRR AHDA VLTL TRHC PSEG SVLD SLRR AQER RELP SDLN LQQV SPLF GTI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | LCA; CACD; CG-E; CYGD; LCA1; RCD2; CACD1; CORD5; CORD6; GUC2D; ROSGC; retGC; CSNB1I; GUC1A4; RETGC-1; ROS-GC1; GUCY2D |
Positive Sample: | Mouse brain,Mouse spinal cord,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 120kDa |
Observed MW: | 95kDa |
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Purification Method: | Affinity purification |
Gene ID: | 3000 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |