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GUCY2C Rabbit Polyclonal Antibody (CAB10562)

SKU:
CAB10562
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:GUCY2C Rabbit Polyclonal Antibody
SKU:CAB10562
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-330 of human GUCY2C (NP_004954.2).
Sequence:SQVS QNCH NGSY EISV LMMG NSAF AEPL KNLE DAVN EGLE IVRG RLQN AGLN VTVN ATFM YSDG LIHN SGDC RSST CEGL DLLR KISN AQRM GCVL IGPS CTYS TFQM YLDT ELSY PMIS AGSF GLSC DYKE TLTR LMSP ARKL MYFL VNFW KTND LPFK TYSW STSY VYKN GTET EDCF WYLN ALEA SVSY FSHE LGFK VVLR QDKE FQDI LMDH NRKS NVII MCGG PEFL YKLK GDRA VAED IVII LVDL FNDQ YFED NVTA PDYM KNVL VLTL SPGN SLLN SSFS RNLS PTKR DFAL AYLN GIL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:GC-C; STAR; DIAR6; GUC2C; MECIL; MUCIL; GUCY2C
Positive Sample:HT-29,SW480,Mouse pancreas
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Endoplasmic reticulum membrane, Single-pass type I membrane protein.
Calculated MW:123kDa
Observed MW:123kDa

This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).

Purification Method:Affinity purification
Gene ID:2984
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using GUCY2C antibody (CAB10562) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.

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