Guanylyl Cyclase beta 1 (GUCY1B3) Rabbit Polyclonal Antibody (CAB15276)
- SKU:
- CAB15276
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Guanylyl Cyclase beta 1 (GUCY1B3) Rabbit Polyclonal Antibody |
SKU: | CAB15276 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Guanylyl Cyclase beta 1 (Guanylyl Cyclase beta 1 (GUCY1B3)) (NP_000848.1). |
Sequence: | MYGF VNHA LELL VIRN YGPE VWED IKKE AQLD EEGQ FLVR IIYD DSKT YDLV AAAS KVLN LNAG EILQ MFGK MFFV FCQE SGYD TILR VLGS NVRE FLQN LDAL HDHL ATIY PGMR APSF RCTD AEKG KGLI LHYY SERE GLQD IVIG IIKT VAQQ IHGT EIDM KVIQ QRNE ECDH TQFL IEEK ESKE EDFY EDLD RFEE NGTQ ESRI SPYT FCKA FPFH IIFD RDLV VTQC GNAI YRVL PQLQ PGNC SL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B3; GC-S-beta-1; Guanylyl Cyclase beta 1 (GUCY1B3) |
Positive Sample: | Mouse brain,Rat lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 71kDa |
Observed MW: | 70kDa |
This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2983 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |