The Guanylin Polyclonal Antibody (CAB9820) is a valuable tool for researchers studying guanylin, a peptide hormone involved in ion transport and fluid balance in the intestine. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the guanylin protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for gastrointestinal and endocrinology research.Guanylin plays a crucial role in the regulation of electrolyte and water transport in the gut, making it a key target for studies on gastrointestinal diseases and disorders.
Its involvement in maintaining intestinal homeostasis and influencing fluid secretion underscores its relevance in digestive health research. By elucidating the function of guanylin, researchers can uncover potential therapeutic strategies for conditions such as diarrheal diseases and intestinal disorders.Overall, the Guanylin Polyclonal Antibody offers a reliable tool for investigating the role of guanylin in intestinal physiology and disease, providing valuable insights for the development of novel therapeutic approaches in gastrointestinal healthcare.
Product Name:
GUCA2A Rabbit Polyclonal Antibody
SKU:
CAB9820
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-115 of human GUCA2A (NP_291031.2).
Predicted to enable guanylate cyclase activator activity. Predicted to be involved in positive regulation of guanylate cyclase activity and signal transduction. Predicted to be located in extracellular region.
Purification Method:
Affinity purification
Gene ID:
2980
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GUCA2A antibody (CAB9820) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 5s.