The Guanylate Kinase Polyclonal Antibody (CAB8656) is a valuable tool for researchers studying guanylate kinase, an enzyme involved in the maintenance of cellular function and signaling pathways. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the guanylate kinase protein, this antibody allows for detection and analysis in various cell types, making it an ideal choice for studies in molecular biology and cell signaling research.Guanylate kinase is a key player in the regulation of nucleotide metabolism and cell proliferation, making it a potential target for therapeutic interventions in diseases such as cancer and neurodegenerative disorders.
Understanding the function and regulation of guanylate kinase is essential for unlocking its potential in the development of novel treatments and therapies. By using the Guanylate Kinase Polyclonal Antibody (CAB8656), researchers can gain valuable insights into the role of this enzyme in cellular processes and disease pathways.
Product Name:
GUK1 Rabbit Polyclonal Antibody
SKU:
CAB8656
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human GUK1 (NP_000849.1).
The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2987
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GUK1 antibody (CAB8656) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
