The GTSE1 Polyclonal Antibody (CAB13902) is a valuable tool for researchers studying GTSE1, a protein involved in cell cycle regulation and cancer progression. This antibody, produced in rabbits, is highly specific to human samples and is optimized for use in immunofluorescence and immunohistochemistry applications. By targeting the GTSE1 protein, this antibody enables precise detection and localization of the protein in various cell types, making it ideal for studies in oncology and cell biology.GTSE1, also known as G2 and S phase-expressed protein 1, plays a crucial role in controlling cell division and DNA damage response mechanisms.
Dysregulation of GTSE1 expression has been linked to tumor development and progression, making it a promising target for cancer research. Understanding the functions of GTSE1 can provide insights into tumor biology and potential therapeutic interventions for cancer treatment.The GTSE1 Polyclonal Antibody is a valuable tool for researchers seeking to explore the role of GTSE1 in cancer biology and cell cycle regulation. Its high specificity and sensitivity make it an essential reagent for studies aiming to unravel the molecular mechanisms underlying tumorigenesis and identify novel targets for anti-cancer therapies.
Product Name:
GTSE1 Rabbit Polyclonal Antibody
SKU:
CAB13902
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human GTSE1 (NP_057510.4).
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
Purification Method:
Affinity purification
Gene ID:
51512
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GTSE1 Rabbit pAb (CAB13902) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
