The GTPBP4 Rabbit Monoclonal Antibody (CAB4743) is a cutting-edge tool for researchers studying GTPBP4, a protein involved in GTP binding and RNA processing. This monoclonal antibody is produced in rabbits and is highly specific for human samples, making it an excellent choice for Western blot applications. By binding to the GTPBP4 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an invaluable asset for studies in cell biology and RNA processing.GTPBP4 plays a crucial role in GTP binding and RNA metabolism, making it a key player in processes such as translation and RNA maturation.
Understanding the function and regulation of GTPBP4 is essential for unraveling its role in cell biology and potential implications in diseases such as cancer and genetic disorders. With its high specificity and sensitivity, the GTPBP4 Rabbit Monoclonal Antibody (CAB4743) is a powerful tool for researchers investigating GTPBP4 and its functions in cellular processes.
Product Name:
GTPBP4 Rabbit Monoclonal Antibody
SKU:
CAB4743
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-92 of human GTPBP4 (Q9BZE4).
GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
Purification Method:
Affinity purification
Gene ID:
23560
Clone Number:
ARC1115
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using GTPBP4 Rabbit mAb (CAB4743) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
