GTPBP4 Rabbit Polyclonal Antibody (CAB4565)
- SKU:
- CAB4565
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GTPBP4
- CRFG
- NGB
- NOG1
- Research Area:
- Cell Biology
Description
Product Name: | GTPBP4 Rabbit Polyclonal Antibody |
SKU: | CAB4565 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 385-634 of human GTPBP4 (NP_036473.2). |
Sequence: | RKRM ETEE SRKK RERD LELE MGDD YILD LQKY WDLM NLSE KHDK IPEI WEGH NIAD YIDP AIMK KLEE LEKE EELR TAAG EYDS VSES EDEE MLEI RQLA KQIR EKKK LKIL ESKE KNTQ GPRM PRTA KKVQ RTVL EKEM RSLG VDMD DKDD AHYA VQAR RSRS ITRK RKRE DSAP PSSV ARSG SCSR TPRD VSGL RDVK MVKK AKTM MKNA QKKM NRLG KKGE ADRH VFDM KPKH LLSG KRKA GKKD RR |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NGB; CRFG; NOG1; GTPBP4 |
Positive Sample: | 293T,HeLa,Jurkat,MCF7,HT-1080,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleolus. |
Calculated MW: | 74kDa |
Observed MW: | 74kDa |
GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
Purification Method: | Affinity purification |
Gene ID: | 23560 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |