The GTPBP1 Polyclonal Antibody (CAB15359) is a crucial tool for researchers studying GTPBP1, a protein involved in cellular processes such as ribosome biogenesis and mitochondrial translation. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for Western blot applications. By targeting the GTPBP1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential resource for studies in molecular biology and mitochondrial function.
GTPBP1, also known as GTP binding protein 1, plays a key role in maintaining cellular homeostasis by regulating protein synthesis and mitochondrial function. Its involvement in essential cellular processes makes it a valuable target for research into diseases such as mitochondrial disorders, cancer, and neurodegenerative diseases. By understanding the function of GTPBP1, researchers can uncover potential therapeutic targets for these conditions and improve treatment strategies.
Product Name:
GTPBP1 Rabbit Polyclonal Antibody
SKU:
CAB15359
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 10-280 of human GTPBP1 (NP_004277.2).
This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype.
Purification Method:
Affinity purification
Gene ID:
9567
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GTPBP1 Rabbit pAb (CAB15359) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.