The GTF3C6 Polyclonal Antibody (CAB13233) is a valuable tool for researchers studying GTF3C6, a key factor in transcription and gene expression regulation. This antibody is produced in rabbits and exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications. By binding to the GTF3C6 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component in studies related to transcriptional regulation and gene expression.GTF3C6, also known as General Transcription Factor IIIC Subunit 6, is crucial for the initiation of transcription by RNA polymerase III.
Its role in regulating gene expression makes it a key player in various biological processes, such as cell growth, differentiation, and development. Research into GTF3C6 can provide valuable insights into molecular mechanisms underlying disease states, such as cancer, genetic disorders, and developmental abnormalities, ultimately leading to the development of targeted therapies and interventions. The GTF3C6 Polyclonal Antibody is a valuable tool for researchers seeking to uncover the functional significance of GTF3C6 in health and disease.
Product Name:
GTF3C6 Rabbit Polyclonal Antibody
SKU:
CAB13233
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human GTF3C6 (NP_612417.1).
RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.
Purification Method:
Affinity purification
Gene ID:
112495
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GTF3C6 Rabbit pAb (CAB13233) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
