The GTF3C4 Polyclonal Antibody (CAB9287) is an essential tool for researchers studying GTF3C4, a key player in transcription initiation and regulation. This highly reactive antibody, produced in rabbits, is specifically designed for use with human samples and has been validated for optimal performance in Western blot applications. By binding to the GTF3C4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it a valuable tool for studies in molecular biology and gene expression.GTF3C4, also known as general transcription factor IIIC subunit 4, is involved in the recruitment of RNA polymerase III to its target genes, playing a crucial role in the initiation of transcription.
Understanding the function and regulation of GTF3C4 is essential for unraveling the complexities of gene expression and transcriptional control. Research into GTF3C4 has implications for various fields, including cancer biology, developmental biology, and epigenetics, making this polyclonal antibody a valuable resource for scientists investigating the molecular mechanisms underlying gene transcription.
Product Name:
GTF3C4 Rabbit Polyclonal Antibody
SKU:
CAB9287
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 583-822 of human GTF3C4 (NP_036336.2).
Predicted to enable enzyme activator activity. Predicted to contribute to DNA binding activity. Predicted to be involved in 5S class rRNA transcription by RNA polymerase III and tRNA transcription by RNA polymerase III. Located in mitochondrion and nucleoplasm. Part of transcription factor TFIIIC complex.
Purification Method:
Affinity purification
Gene ID:
9329
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GTF3C4 antibody (CAB9287) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.