GTF3C2 Antibody (PACO01613)
- SKU:
- PACO01613
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
GTF3C2 Antibody (PACO01613)
The GTF3C2 Polyclonal Antibody (PACO01613) is a valuable tool for researchers studying GTF3C2, a key transcription factor involved in RNA polymerase III transcription. This antibody is produced in rabbits and exhibits high specificity and reactivity with human samples, making it suitable for use in Western blot applications. By binding to the GTF3C2 protein, this antibody allows for precise detection and analysis in various cell types, enabling in-depth research in the fields of molecular biology and gene regulation.GTF3C2 is a vital component of the RNA polymerase III transcription machinery, playing a crucial role in the regulation of gene expression.
Understanding the function of GTF3C2 is essential for unraveling the complex mechanisms underlying transcriptional control and its impact on cellular processes. Research utilizing the GTF3C2 Polyclonal Antibody can provide valuable insights into gene regulation, transcriptional activity, and the development of potential therapeutic strategies targeting RNA polymerase III-associated disorders.
| Antibody Name: | GTF3C2 Antibody |
| Antibody SKU: | PACO01613 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the N-terminal region of human TFIIIC110. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | GTF3C2; KIAA0011; General transcription factor 3C polypeptide 2; TF3C-beta; Transcription factor IIIC 110 kDa subunit; TFIIIC 110 kDa subunit; TFIIIC110; Transcription factor IIIC subunit beta |
| UniProt Protein Function: | GTF3C2: Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription initiation complex Chromosomal Location of Human Ortholog: 2p23.3 Cellular Component: nucleoplasm; transcription factor TFIIIC complex Molecular Function:DNA binding Biological Process: 5S class rRNA transcription; gene expression; transcription from RNA polymerase III promoter; transcription, DNA-dependent; tRNA transcription from RNA polymerase III promoter |
| UniProt Code: | Q8WUA4 |
| NCBI GenInfo Identifier: | 48428661 |
| NCBI Gene ID: | 2976 |
| NCBI Accession: | Q8WUA4.2 |
| UniProt Secondary Accession: | Q8WUA4,Q16632, Q9BWI7, D6W557, |
| UniProt Related Accession: | Q8WUA4 |
| Molecular Weight: | 64,003 Da |
| NCBI Full Name: | General transcription factor 3C polypeptide 2 |
| NCBI Synonym Full Names: | general transcription factor IIIC subunit 2 |
| NCBI Official Symbol: | GTF3C2Â Â |
| NCBI Official Synonym Symbols: | TFIIIC110; TFIIIC-BETAÂ Â |
| NCBI Protein Information: | general transcription factor 3C polypeptide 2 |
| UniProt Protein Name: | General transcription factor 3C polypeptide 2 |
| UniProt Synonym Protein Names: | TF3C-beta; Transcription factor IIIC 110 kDa subunit; TFIIIC 110 kDa subunit; TFIIIC110; Transcription factor IIIC subunit beta |
| Protein Family: | General transcription factor 3C polypeptide |
| UniProt Gene Name: | GTF3C2Â Â |
| UniProt Entry Name: | TF3C2_HUMAN |
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