GTF2IRD1 Polyclonal Antibody (CAB24506)
- SKU:
- CAB24506
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
| Product Name: | GTF2IRD1 Polyclonal Antibody |
| SKU: | CAB24506 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-890 of human GTF2IRD1 (NP_057412.1). |
| Sequence: | SLGF SPPA LPPE RDSG DPLV DESL KRQG FQEN YDAR LSRI DIAN TLRE QVQD LFNK KYGE ALGI KYPV QVPY KRIK SNPG SVII EGLP PGIP FRKP CTFG SQNL ERIL AVAD KIKF TVTR PFQG LIPK PDED DANR LGEK VILR EQVK ELFN EKYG EALG LNRP VLVP YKLI RDSP DAVE VTGL PDDI PFRN PNTY DIHR LEKI LKAR EHVR MVII NQLQ PFAE ICND AKV |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:100 - 1:500 |
| Synonyms: | GTF2IRD1; BEN; CREAM1; GTF3; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12; hMusTRD1alpha1; GTF2I repeat domain containing 1 |
| Positive Sample: | Rat liver |
| Conjugate: | Unconjugated |
| Cellular Localization: | Nucleus |
| Calculated MW: | 104kDa/106kDa/107kDa |
| Observed MW: | 130kDa |
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
| Purification Method: | Affinity purification |
| Gene ID: | 9569 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of Rat liver, using GTF2IRD1 Rabbit pAb (CAB24506) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s. |
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