GTF2IRD1 Rabbit Polyclonal Antibody (CAB6613)
- SKU:
- CAB6613
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | GTF2IRD1 Rabbit Polyclonal Antibody |
SKU: | CAB6613 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-959 of human GTF2IRD1 (NP_057412.1). |
Sequence: | SLGF SPPA LPPE RDSG DPLV DESL KRQG FQEN YDAR LSRI DIAN TLRE QVQD LFNK KYGE ALGI KYPV QVPY KRIK SNPG SVII EGLP PGIP FRKP CTFG SQNL ERIL AVAD KIKF TVTR PFQG LIPK PDED DANR LGEK VILR EQVK ELFN EKYG EALG LNRP VLVP YKLI RDSP DAVE VTGL PDDI PFRN PNTY DIHR LEKI LKAR EHVR MVII NQLQ PFAE ICND AKVP AKDS SIPK RKRK RVSE GNSV SSSS SSSS SSSS NPDS VASA NQIS LVQW PMYM VDYA GLNV QLPG PLNY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BEN; WBS; GTF3; RBAP2; CREAM1; MUSTRD1; WBSCR11; WBSCR12; hMusTRD1alpha1; GTF2IRD1 |
Positive Sample: | 293T,HeLa,BT-474,SW480,Mouse ovary,Mouse thymus,Rat kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 106kDa |
Observed MW: | 106kDa |
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 9569 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |