The GTF2I Polyclonal Antibody (CAB7898) is a valuable tool for researchers studying GTF2I, a transcription factor involved in gene regulation and development. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GTF2I protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and developmental biology.GTF2I, also known as general transcription factor II-I, plays a crucial role in the regulation of gene expression and plays a key role in cell differentiation and growth.
Understanding the function of GTF2I is essential for unraveling the complexities of gene regulation and developmental processes. Research on GTF2I has implications for a wide range of biological processes, including embryonic development, cell signaling, and disease mechanisms. By using the GTF2I Polyclonal Antibody (CAB7898), researchers can delve deeper into the functions and interactions of this important transcription factor, paving the way for new insights and discoveries in the field of molecular biology.
Product Name:
GTF2I Rabbit Polyclonal Antibody
SKU:
CAB7898
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 600-810 of human GTF2I (NP_001157108.1).
This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
2969
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from BT-474 cells, using GTF2I Rabbit pAb (CAB7898) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
