The GTF2H4 Polyclonal Antibody (CAB8425) is a valuable tool for research involving the GTF2H4 protein, a key component of the transcription factor IIH (TFIIH) complex. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the GTF2H4 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and gene regulation.
GTF2H4 is essential for transcription initiation and DNA repair processes, playing a critical role in maintaining genome stability and regulating gene expression. Its involvement in these crucial cellular functions makes it a target of interest in research on cancer, neurodegenerative diseases, and other genetic disorders. Understanding the function and regulation of GTF2H4 is essential for unraveling the complexities of gene transcription and DNA damage response pathways.
Product Name:
GTF2H4 Rabbit Polyclonal Antibody
SKU:
CAB8425
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GTF2H4 (NP_001508.1).
Enables RNA polymerase II general transcription initiation factor activity. Involved in transcription by RNA polymerase II. Located in nuclear speck. Part of core TFIIH complex portion of holo TFIIH complex and transcription factor TFIID complex.
Purification Method:
Affinity purification
Gene ID:
2968
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GTF2H4 antibody (CAB8425) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
